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codeine is not itself centrally active, and must first be converted via first pass metabolism into morphine by the cytochrome p450 enzyme cyp2d6 (as such, it is a prodrug for morphine). codeine is also metabolised into the inactive norcodeine via the cyp3a4 enzyme system. both resultant forms are conjugated by ugt2b7 into their corresponding 3-glucuronide.

bulk discount:
1 Gram10.15
3 Grams23.00
5 Grams31.50
10 Grams61.00
25 Grams139.50
50 Grams254.00
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