3C-E

3,5-dimethoxy-4-ethoxyamphetamine (commonly known as 3c-e or 3c-escaline) is a synthetic psychedelic compound of the amphetamine chemical class. although its name suggests it may be related to the 2c-x family, this is not the case since it is the 3-carbon analog of escaline

it was presumably first synthesized by alexander shulgin and published in his book pihkal in 1991.

today, 3c-e is used for recreational and research purposes, and exclusively distributed as a gray area research chemical by online vendors. very little is known about its effects besides its strong body high and weak visuals.

chemistry

3c-e or 3,5-dimethoxy-4-ethoxyamphetamine, is a molecule of the substituted amphetamine class. amphetamines are substituted phenethylamines containing a phenyl ring bound to an amino (nh₂) group through an ethyl chain and a methyl group bound to the alpha carbon r_α. 3c-e contains methoxy functional groups och₃ attached to carbons r₃ and r₅ and an ethoxy chain och₂ch₃ attached to carbon r₄ of the phenyl ring.

3c-e is the amphetamine analog of escaline.

pharmacology

3c-e’s psychedelic effects are believed to come from its efficacy at the 5-ht_2a receptor as a partial agonist. however, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.