DPT

n,n-dipropyltryptamine (also known as dipropyltryptamine, dpt, and “the light”) is a lesser-known psychedelic substance of the tryptamine class. it is closely related to dmt and is reported to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration and greater unpredictability relative to dmt and other psychedelic tryptamines.

dpt was first synthesized in 1950. human use was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism. it has also been researched in high doses to induce peak experiences for terminal cancer patients. it has gained some notoriety for its adoption as the primary sacrament for the “temple of the true inner light” in the united states, a christian off-shoot organization who believe in the ritual use of psychedelics and refer to them as “the true flesh of god.”

dpt is commonly consumed via insufflation or orally. many report the experience of insufflation to be very congestive and painful which, with the rapidness of onset, does not give the user much time to acclimate themselves to its powerful effects. it can also be administered intramuscularly or via vaporization after conversion to the freebase form. smoking the freebase is reported to be the preferred route used by the “temple of true inner light”.

very little data exists about the pharmacological properties, metabolism, and toxicity of dpt, and it has relatively little history of human usage. it has long been available on the research chemicals market as a legal, grey-market alternative to dmt, and commercially distributed through online vendors. many reports also suggest that this substance may be overly difficult to use safely for those who are not already very experienced with hallucinogens. it is highly advised to approach this powerful psychedelic substance with the proper amount of precaution and harm reduction practices when using it.

chemistry

dpt, or n,n-dipropyltryptamine, is a synthetic indole molecule of the tryptamine class. tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at r₃ to an amino group via an ethyl side chain. dpt contains two propyl groups carbon chains bound to the terminal amine r_n of its tryptamine backbone.

dpt has a number of substituted analogs such as 4-ho-dpt or 4-aco-dpt.

pharmacology

dpt’s psychedelic effects are believed to come from its efficacy at the 5-ht_2a and 5-ht_1a receptor as a partial agonist.

the role of these interactions and how they result in the psychedelic experience remains the subject of ongoing scientific investigation.